presentation: Painful distal thigh ?prox. leg swelling/mass.
Examination: -mass examination: -site -shape -size -tenderness -temperature changes -surface -consistency -border -?sinus,ulceration,discharge -special features -pulsatile/expansile -translumination test -bruit -relation to adjacent structures -attachment to skin and underlying muscles -mobility -compression effects to neurovascular structure -knee joint ROM
Common Qs: 1.Differential diagnosis: -tumor -osteosarcoma -infection -chronic OMof prox tibia -TB -TB arthritis - usually the sweeling is diffuse and ROMknee is usually present.
2.Investigations -Blood: -Hb - anemia - nonspecific -TWDC -elevated in infection -ESR -non specific -LFT -elevated ALP - suggestive of bone tumor -Radiological:(Radiological staging) -Plain x-ray of the affected limb -osteolytic changes, cortical destruction,periosteal elevation(Codman's triangle), narrow zone of transistion (both present in tumor and Chronic OM) -calcification/new bone formation - more toward sbone forming tumor eg osteosarcoma. -look for joint involvement, skip lesion into femur -pathological fracture -Chest x ray - look for secondary -Other investigation: -MRI - soft tissue involvement - marrow extension, muscles and neurovascular
involvement -CT scan - the affected site (for cortical destruction) - chest especially if plain chest x ray is normal - TRO secondaries -Bone scan - to detect secondaries -angiogram if necessary
3.What is next? -Biopsy.(histological staging)
4.What is tumor staging - Full radiological staging & biopsy . -for diagnosis and localization of tumor
6.How do you treat the tumor? generally depends on: - histological diagnosis -tumor grading Options:general principles -surgical resection - localized tumor without mets. -chemotherapy- tumor with mets. /certain tumor eg Ewing's sarcoma -radiotherapy- surgically inaccesible tumor eg.pelvis, spine #sometimes used in combination